Summary of claims: RR1 is a novel α-D-glucan polysaccharide composed
of a (1→4) linked back bone and (1→6) linked branches. RR1 exhibits
unique immune-stimulating properties and is non-cytotoxic. The subject invention
also concerns compositions containing an RR1 compound and methods for modulating an immune response in a subject using RR1
Nair PKR, Rodriguez S, Ramachandran R, Alamo A, Melnick, SJ, Escalon E, Garcia PI, Wnuk
SF, Ramachandran, C. Immune stimulating properties of a novel polysaccharide from the
medicinal plant Tinospora cordifolia. International Immunopharmacology. 2004;4:1645-1659.
Nair, PKR, Melnick SJ, Ramachandran R; Escalon E, Ramachandran C. Mechanism of Immune System
Activation by (1,4)-α-D-glucan from Tinospora cordifolia. International Immunopharmacology. 2005;6:1815-1824.